FLUOROCHROMES FITC, PE, PERCP-CY5.5, APC, AL. FLUOR 700.

The monoclonal antibody is directed against the CD24 antigen, which is expressed on virtually all B-cells: early B-cell precursors, pre-pre-B-cells, pre-B-cells, B- cells, intermediate B-cells, mature B-cells and some plasmacytoid cells are positive while plasma cells are negative. The monoclonal antibody reacts with human granulocytes and their precursors (from promyelocytic stage). The monoclonal antibody also reacts with virtually all pre-B-cell lines and Burkitt cell lines, but is only expressed on less then 50% of the B-cell lymphoblastoid cell lines. Non T-ALL, B-cell NHL and 50% of myelomas as well as a subpopulation of AML is found to be positive. Hairy Cell Leukaemia is found to be weakly positive.