Reagents

Biological Reagents

Consumables

Consumables

Instruments

Flow Cytometers

Culture Dishes

Culture Dishes

CD11B MONOCLONAL ANTIBODY

FLUOROCHROMES FITC, ALEXA FLUOR 488, PE, PERCP, APC, CF-BLUE, OC515. CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.

logosm-biog
16 Evripidou street, 56224 Thessaloniki

Thessaloniki office tel:   +30 2310 558 888  
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Athens office tel: +30 6956 768 939 
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