Reagents

Biological Reagents

Consumables

Consumables

Instruments

Flow Cytometers

Culture Dishes

Culture Dishes

CD117 MONOCLONAL ANTIBODY
CD117  MONOCLONAL ANTIBODY

FLUOROCHROME FITC, PE, PE-CY5, PERCP-CY5.5, PE-CY7, APC

CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.

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16 Evripidou street, 56224 Thessaloniki

Thessaloniki office tel:   +30 2310 558 888  
Thessaloniki office fax:  +30 2310 558 888

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Athens office tel: +30 6956 768 939 
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